Lamp2b蛋白
TīmeklisThe lysosomal membrane proteins LAMP-1 and LAMP-2 are estimated to contribute to about 50% of all proteins of the lysosome membrane. Surprisingly, mice deficient in … Tīmeklis内质网(er)是分泌蛋白进行翻译后修饰和正确折叠的过程的场所。为了获得分泌蛋白的天然构象,许多分泌蛋白需要形成分子内或分子间二硫键。 这个过程叫做氧化蛋白 …
Lamp2b蛋白
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TīmeklisWestern blot analysis of extracts of various cell lines, using LAMP2 Rabbit mAb (A0593) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) … Tīmeklis利用携带软骨细胞的亲合肽(CAP)融合表达展示于外泌体膜蛋白(lamp2b)上表面作为靶向的基因工程化外泌体可实现靶向软骨细胞(图1)。与无靶向的天然外泌体相 …
Tīmeklis2024. gada 3. dec. · Lung cancer is the major cause of cancer-related deaths globally. Mutant KRAS is a feature of 15–50% of lung cancer cases and represents one of the most prevalent oncogenic drivers in this disease. Unfortunately, although much effort has been spent on searching for small molecule inhibitors of KRAS, KRAS gene has … Tīmeklis2024. gada 23. jūn. · bamboopiggy. LAMP2基因9号外显子的剪切差异可致所编码的LAMP2蛋白存在LAMP2A、LAMP2B及LAMP2C 3种亚型,区别仅在于溶酶体羧基末端跨膜区域及胞浆短尾。. LAMP2A及LAMP2C在全身各组织中广泛表达,而LAMP2B则选择性地在心肌、骨骼肌及脑组织中高水平表达.
Tīmeklis蛋白质印迹法实验步骤. 蛋白质印迹法就是将膜与 5% w/v 脱脂奶粉、1X TBS 以及 0.1% Tween ® 20 中的稀释的一抗在 4°C 下进行夜间孵育,同时轻轻晃动。. 注意:请参阅一抗产品网页了解推荐的抗体稀释度。. A. 溶液与试剂. 注:使用反渗透去离子水 (RODI) 或同等级别的水配制溶液。 Tīmeklis研究mirna的靶点mrna,构建过表达质粒,是否需要考虑3‘utr区,还是只过表达cds区就行了?. rt,因为mirna和mrna的3’utr区结合,过表达是仅过表达cds区是不是没有效果?是不是要包含3‘utr区?. 丁香园-核酸基因技术-2024-05-03 09:48:59
Tīmeklis2024. gada 3. apr. · 公开资料显示,盐酸环丙沙星氟轻松滴耳液是一款治疗耳道炎的产品,已在美国、加拿大、欧盟、中国香港等多个国家和地区获得批准上市。 2月9日,药监局官网显示,辉瑞枸橼酸托法替布缓释片的新适应症获批上市。
Tīmeklis2024. gada 24. aug. · 他们首先转导 DC 以表达外泌体膜蛋白 LAMP2B,该蛋白能与神经元特异性 RVG 肽融合。纯化的 DC 外泌体中装有靶向 BACE1(阿尔茨海默病的发病机理中的重要调控基因)的外源 siRNA,然后将这些 iExosome 静脉注射到小鼠体内。 graphite companies in north americaTīmeklis2024. gada 25. marts · In addition, images also showed that LAMP2B colocalization with LAMP2A is lower than expected (73.88 ± 13.09%), indicating that both LAMP2 isoforms are often segregated into different vesicles (fig. S6C). Overall, our evidence indicates that LAMP2A, but not LAMP2B, participates in the loading of proteins containing … chisamba protea hotelTīmeklis2024. gada 6. aug. · rvg-lamp2b融合蛋白被转运到细胞膜,在细胞膜内陷形成外泌体时便将rvg展示在外泌体的表面。通过对过表达cd10-dm和rvg的细胞的培养,使细胞在生长和增殖过程中大量分泌含有cd10-dm、表面展示rvg短肽的外泌体到培养基中;再经分离提纯,得到装载有大量cd10-dm、表面 ... graphite companies on the asxTīmeklis2024. gada 8. janv. · Here, we identify the LAMP-2 isoform B (LAMP-2B) as required for autophagosome-lysosome fusion in human cardiomyocytes (CMs). Remarkably, LAMP-2B functions independently of syntaxin 17 (STX17), a protein that is essential for autophagosome-lysosome fusion in non-CMs. Instead, LAMP-2B interacts with … graphite companies in canadaTīmeklisLAMP2. Lysosome-associated membrane protein 2 ( LAMP2 ), also known as CD107b ( C luster of D ifferentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins . The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides … graphite compound gasketTīmeklisLAMP1 (D2D11) XP ® Rabbit mAb 可识别 LAMP1 总蛋白的内源水平。 物种反应性: 人, 猴 来源/纯化 使用人 LAMP1 蛋白的重组蛋白片段对动物进行免疫接种来产生单克隆 … graphite companies stockTīmeklis他们首先转导 DC 以表达外泌体膜蛋白 LAMP2B,该蛋白能与神经元特异性 RVG 肽融合。纯化的 DC 外泌体中装有靶向 BACE1(阿尔茨海默病的发病机理中的重要调控基因)的外源 siRNA,然后将这些 iExosome 静脉注射到小鼠体内。 chisami-early morning sweatpants