WebIRF3 and IRF7 were altered in 5% and 6% of all TCGA STAD patients. Further analysis revealed that IRF7 was significantly associated with the abundance of immune cells (B cells, Neutrophils and Dendritic cells) and the expression of most immune biomarkers. Enrichment analysis indicated that IRF7 was mainly involved in adaptive immune response ... WebInterferon regulatory factor 7 (IRF7) is a transcription factor involved in the activation of the type I IFN response upon pathogenic infection [1, 2]. IRF7 is constitutively expressed by plasmacytoid dendritic cells (pDCs), which are known as ‘professional’ type I …
IRF-7 Antibody Cell Signaling Technology
• Ning S, Pagano JS, Barber GN (September 2011). "IRF7: activation, regulation, modification and function". Genes and Immunity. 12 (6): 399–414. doi:10.1038/gene.2011.21. PMC 4437765. PMID 21490621. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S030… • Ning S, Pagano JS, Barber GN (September 2011). "IRF7: activation, regulation, modification and function". Genes and Immunity. 12 (6): 399–414. doi:10.1038/gene.2011.21. PMC 4437765. PMID 21490621. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S0300-9084(99)80018-2. PMID 9865487. WebIRF-7 plays an essential role in the induction of type I interferon in response viral infecton (6-8). Like IRF-3, IRF-7 is regulated at multiple serine phosphorylation sites near its … so many beers so little time
Single-cell RNA-seq reveals new types of human blood dendritic cells …
WebMar 7, 2024 · IRF7 has been widely studied in inflammatory models [ 12 ], while its suppressive effects in malignancies are mainly accomplished by microenvironmental immune cells, including granulocytic... WebApr 14, 2011 · expressed and stable in most cells, IRF7 remains at low. levels in most cell types, and has a very short half-life. of 0.5 B 1 h in infected cells and approximately 5 h in. WebDec 13, 2024 · IRF7 silencing sensitizes tumor cells to chemotherapy in vitro and breaks dormancy in vivo To functionally validate the role of IRF7 in tumor dormancy, we stably silenced IRF7 expression in... small businesses that are easy to start