WebGrapefruit juice can raise the plasma levels of simvastatin and may increase the risk of myopathy and rhabdomyolysis. ... linkage study of 1152 statin-exposed pregnant women compared to 886,996 controls did not find a significant teratogenic effect from maternal use of statins in the first trimester of pregnancy, after adjusting for potential ... WebMar 29, 2024 · Grapefruit contains nutrients and antioxidants shown to help protect the heart by regulating blood pressure and cholesterol levels. 6. It’s high in powerful antioxidants. Grapefruit contains a ...
Zocor: Uses, Dosage, Side Effects & Warnings - Drugs.com
http://pcmc2024.ciu.edu.tr/en/student-life/campus-services/drug-information-center/grapefruit-juice-and-drug-interactions WebMar 10, 2024 · The FDA confirmed that mixing grapefruit and statins could lead to an increased risk for liver and muscle damage. These two side effects may even lead to kidney failure, which is a serious... gotcha grill
Statins and Grapefruit Interactions: Risks and Side Effects
WebDec 31, 2024 · What is known is that statin drug levels can increase by anywhere from 80 percent to 260 percent if the medication is taken at … WebConsumption of grapefruit or grapefruit juice inhibits the metabolism of certain statins, and bitter oranges may have a similar effect. Furanocoumarins in grapefruit juice (i.e. bergamottin and dihydroxybergamottin) inhibit the cytochrome P450 enzyme CYP3A4, which is involved in the metabolism of most statins (however, it is a major inhibitor ... chiefs colts playoff history