WebJul 1, 2024 · Consequently, a proportion of the participants who achieved the female range testosterone (<50 ng/dL) was significantly higher in cyproterone acetate group (90%) … WebJul 1, 2024 · Methods. The study was single-blinded randomized controlled trial involved 52 transgender women from two transgender health clinics. Each participant received oral estradiol valerate 4 mg/day combined with anti-androgen, spironolactone 100 mg/day or cyproterone acetate 25 mg/day, depending on which group they were randomized to.

Cyproterone vs spironolactone as anti-androgen therapy for …

WebJun 11, 2024 · The cyproterone group achieved serum total testosterone concentrations in the female reference range, and as spironolactone may cause feminisation without inhibition of steroidogenesis, it is unclear which anti-androgen is more effective at feminisation. Background Oestradiol with or without an anti-androgen (cyproterone … WebJul 1, 2024 · Evidence regarding testosterone suppression efficacy of spironolactone are conflicting in many literatures. 5, 7, 17 In this study, the change of testosterone levels … chk investment forum

Hormone therapy for trans and gender diverse patients …

WebEffective dosages are 100 mg daily in postmenopausal women, and 50 mg for 10 days in premenopausal women for three months. 4 In one study of 80 patients, cyproterone produced similar results to 200 mg daily of spironolactone. 5 This is a pregnancy category X medication as it may cause feminisation of the male fetus. 14 Side effects include ... WebNational Center for Biotechnology Information WebJan 1, 2000 · Spironolactone and cyproterone acetate are the antiandrogens most commonly used in the treatment of hirsutism. Both of these steroidal compounds … grass pokemon in platinum