WebJun 1, 2024 · CCCTC-binding factor (CTCF) plays indispensable roles in transcriptional inhibition/activation, insulation, gene imprinting, and regulation of 3Dchromatin structure. … Web14 hours ago · It is confirmed that the cis-regulatory elements may be indispensable drivers of phenotypic variation of domesticated animals, given the facts that ... [110,111,112,113], while the looped enhancers were drastically enriched for motifs of CTCF and key myogenic regulators, such as MEF2, KLF, MyoD, and MyoG. We then integrated Hi-C interaction ...
Roles of CTCF in conformation and functions of …
WebJun 5, 2015 · CTCF also helps chromatin attach to the nuclear matrix and form functionally distinct regions called topological domains. 21 Using ChIP, CTCF was shown to bind numerous genomic sites, 22 many... WebJul 16, 2024 · We studied CTCF binding by chromatin immunoprecipitation sequencing in cells from patients with acute myeloid leukemia (AML) and in normal bone marrow (NBM) in the context of gene expression, DNA methylation, and azacitidine exposure. CTCF binding was increased in AML compared with NBM. daft share rochestown cork
CTCF acetylation at lysine 20 is required for the early cardiac ...
WebMar 21, 2024 · CTCF (CCCTC-Binding Factor) is a Protein Coding gene. Diseases associated with CTCF include Intellectual Developmental Disorder, Autosomal Dominant 21 and Acute Megakaryoblastic Leukemia In Down Syndrome.Among its related pathways are RNA Polymerase I Promoter Opening and Nervous system development.Gene Ontology … WebMay 5, 2024 · The CCCTC binding factor (CTCF) is an 11 zinc finger protein expressed ubiquitously (Klenova et al. 1993 ). It has multiple functions and is associated with … WebBackground: The transcription factor CTCF appears indispensable in defining topologically associated domain boundaries and maintaining chromatin loop structures within these … daft share cork